As an NMR spectroscopist, there is really nothing better than getting your first glimpse of the 2D 1H-15N NMR spectrum of your particular protein known as the HSQC (heteronuclear single quantum coherence). This spectrum gives us a 'fingerprint' of the protein backbone that we use to study dynamics and interactions with small molecules and other proteins. Each peak here represents a backbone amide for one non-proline amino acid, allowing us to probe the environment of our prot
Our heartiest congratulations to Alicia, who successfully defended her Ph.D. thesis on Wednesday. Alicia received an EMBO Long Term Fellowship and is off to study cryo-EM with Nico Thoma's group at the FMI in Basel, Switzerland. We'll miss you, Alicia!